Secondary hemophagocytic lymphohistiocytosis linked to pathogenic microorganisms in pediatrics, pathophysiology and diagnosis: A review.

Secondary hemophagocytic lymphohistiocytosis (s-HLH) is an acute systemic inflammatory disorder caused by uncontrolled activation of the immune system which produces a cytokine storm. This disorder is caused by infections, autoimmune diseases or malignancy and is more prevalent in adults, therefore...