In silico drug repurposing for the identification of potential candidate molecules against arboviruses infection

Arboviral diseases caused by dengue (DENV), Zika (ZIKV) and chikungunya (CHIKV) viruses represent a major public health problem worldwide, especially in tropical areas where millions of infections occur every year. The aim of this research was to identify candidate molecules for the treatment of the...

Full description

Autores:
Tipo de recurso:
Fecha de publicación:
2020
Institución:
Universidad Tecnológica de Bolívar
Repositorio:
Repositorio Institucional UTB
Idioma:
eng
OAI Identifier:
oai:repositorio.utb.edu.co:20.500.12585/9250
Acceso en línea:
https://hdl.handle.net/20.500.12585/9250
Palabra clave:
Antiviral
Chikungunya
Dengue
Virtual screening
Virus entry
Zika
Antrafenine
Conivaptan
Ergotamine
Itraconazole
Natamycin
Nilotinib
Novobiocin
Pranlukast
Viral protein
Antiviral activity
Arbovirus
Article
Chikungunya
Computer model
Crystallography
Dengue
Drug protein binding
Drug repositioning
Fluorescence analysis
Fluorescence microscopy
Huh-7 cell line
Human
Human cell
In vitro study
Priority journal
Virus capsid
Virus entry
Zika fever
Rights
openAccess
License
http://creativecommons.org/licenses/by-nc-nd/4.0/