Amplifying immunogenicity of prospective Covid-19 vaccines by glycoengin- eering the coronavirus glycan-shield to present α-gal epitopes
The many carbohydrate chains on Covid-19 coronavirus SARS-CoV-2 and its S-protein form a glycanshield that masks antigenic peptides and decreases uptake of inactivated virus or S-protein vaccines by APC. Studies on inactivated influenza virus and recombinant gp120 of HIV vaccines indicate that glyco...
- Autores:
- Tipo de recurso:
- Article of investigation
- Fecha de publicación:
- 2020
- Institución:
- Universidad de Bogotá Jorge Tadeo Lozano
- Repositorio:
- Expeditio: repositorio UTadeo
- Idioma:
- eng
- OAI Identifier:
- oai:expeditiorepositorio.utadeo.edu.co:20.500.12010/12299
- Acceso en línea:
- https://doi.org/10.1016/j.vaccine.2020.08.032
http://hdl.handle.net/20.500.12010/12299
- Palabra clave:
- Covid-19
Vaccines
Glycoengineering
Coronavirus
Síndrome respiratorio agudo grave
COVID-19
SARS-CoV-2
Coronavirus
- Rights
- License
- Abierto (Texto Completo)