Sonidegib en el tratamiento del carcinoma basocelular localmente avanzado

Sonidegib is an antagonist of the transmembrane protein Smoothened in the Hedgehog signaling pathway. It is indicated for the treatment of locally advanced basal cell carcinoma (BCC) that is not amenable to curative surgery or radiotherapy. Sonidegib’s efficacy and safety were demonstrated in the ph...

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Autores:
Tipo de recurso:
Article of investigation
Fecha de publicación:
2020
Institución:
Universidad de Bogotá Jorge Tadeo Lozano
Repositorio:
Expeditio: repositorio UTadeo
Idioma:
eng
OAI Identifier:
oai:expeditiorepositorio.utadeo.edu.co:20.500.12010/15707
Acceso en línea:
https://doi.org/doi:10.1016/j.ad.2020.11.002
http://hdl.handle.net/20.500.12010/15707
Palabra clave:
Locally advanced basal cell carcinoma
Sonidegib
Hedgehog signaling pathway
Hedgehog pathway inhibitors
Síndrome respiratorio agudo grave
COVID-19
SARS-CoV-2
Coronavirus
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