Impact of glycan cloud on the B-cell epitope prediction of SARS-CoV-2 Spike protein

The SARS-CoV-2 outbreak originated in China in late 2019 and has since spread to pandemic proportions. Diagnostics, therapeutics and vaccines are urgently needed. We model the trimeric Spike protein, including flexible loops and all N-glycosylation sites, in order to elucidate accessible epitopes fo...

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Autores:
Tipo de recurso:
Article of investigation
Fecha de publicación:
2020
Institución:
Universidad de Bogotá Jorge Tadeo Lozano
Repositorio:
Expeditio: repositorio UTadeo
Idioma:
eng
OAI Identifier:
oai:expeditiorepositorio.utadeo.edu.co:20.500.12010/13396
Acceso en línea:
https://doi.org/10.1038/s41541-020-00237-9
http://hdl.handle.net/20.500.12010/13396
Palabra clave:
SARS-CoV-2
Spike protein
B-cell
Glycan cloud
Síndrome respiratorio agudo grave
COVID-19
SARS-CoV-2
Coronavirus
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License
Abierto (Texto Completo)