Both Boceprevir and GC376 efficaciously inhibit SARS-CoV-2 by targeting its main protease

COVID-19 was declared a pandemic on March 11 by WHO, due to its great threat to global public health. The coronavirus main protease (Mpro, also called 3CLpro) is essential for processing and maturation of the viral polyprotein, therefore recognized as an attractive drug target. Here we show that a c...

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Autores:
Tipo de recurso:
Article of journal
Fecha de publicación:
2020
Institución:
Universidad de Bogotá Jorge Tadeo Lozano
Repositorio:
Expeditio: repositorio UTadeo
Idioma:
eng
OAI Identifier:
oai:expeditiorepositorio.utadeo.edu.co:20.500.12010/13444
Acceso en línea:
https://www.nature.com/articles/s41467-020-18233-x#article-info
http://hdl.handle.net/20.500.12010/13444
https://doi.org/10.1038/s41467-020-18233-x
Palabra clave:
SARS-CoV-2
Síndrome respiratorio agudo grave
COVID-19
SARS-CoV-2
Coronavirus
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