NVX-CoV2373 vaccine protects cynomolgus macaque upper and lower airways against SARS-CoV-2 challenge

There is an urgent need for a safe and protective vaccine to control the global spread of SARS-CoV-2 and prevent COVID-19. Here, we report the immunogenicity and protective efficacy of a SARS-CoV-2 subunit vaccine (NVX-CoV2373) produced from the full-length SARS-CoV-2 spike (S) glycoprotein stabiliz...

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Autores:
Tipo de recurso:
Article of investigation
Fecha de publicación:
2020
Institución:
Universidad de Bogotá Jorge Tadeo Lozano
Repositorio:
Expeditio: repositorio UTadeo
Idioma:
eng
OAI Identifier:
oai:expeditiorepositorio.utadeo.edu.co:20.500.12010/15621
Acceso en línea:
https://doi.org/10.1016/j.vaccine.2020.10.064
http://hdl.handle.net/20.500.12010/15621
Palabra clave:
SARS-CoV-2
COVID-19
Spike glycoprotein
NVX-CoV2373 nanoparticles
Matrix-M adjuvant
Nonhuman primate
COVID-19 (Enfermedad)
Infecciones por coronavirus
Vacunas - Pruebas
Rights
License
Abierto (Texto Completo)