Feline coronavirus drug inhibits the main protease of SARS-CoV-2 and blocks virus replication
The main protease, Mpro (or 3CLpro) in SARS-CoV-2 is a viable drug target because of its essential role in the cleavage of the virus polypeptide. Feline infectious peritonitis, a fatal coronavirus infection in cats, was successfully treated previously with a prodrug GC376, a dipeptide-based protease...
- Autores:
- Tipo de recurso:
- Article of journal
- Fecha de publicación:
- 2020
- Institución:
- Universidad de Bogotá Jorge Tadeo Lozano
- Repositorio:
- Expeditio: repositorio UTadeo
- Idioma:
- eng
- OAI Identifier:
- oai:expeditiorepositorio.utadeo.edu.co:20.500.12010/13433
- Acceso en línea:
- https://www.nature.com/articles/s41467-020-18096-2#article-info
http://hdl.handle.net/20.500.12010/13433
https://doi.org/10.1038/s41467-020-18096-2
- Palabra clave:
- SARS-CoV-2
Síndrome respiratorio agudo grave
COVID-19
SARS-CoV-2
Coronavirus
SARS-CoV-2
Feline coronavirus
- Rights
- License
- Abierto (Texto Completo)