Computer-aided drug design against spike glycoprotein of SARS-CoV-2 to aid COVID-19 treatment

Background: SARS-CoV-2 has the Spike glycoprotein (S) which is crucial in attachment with host receptor and cell entry leading to COVID-19 infection. The current study was conducted to explore drugs against Receptor Binding Domain (RBD) of SARS-CoV-2 using in silico pharmacophore modelling and virtu...

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Autores:

Tipo de recurso:

Article of investigation

Fecha de publicación:

2020

Institución:

Universidad de Bogotá Jorge Tadeo Lozano

Repositorio:

Expeditio: repositorio UTadeo

Idioma:

eng

OAI Identifier:

oai:expeditiorepositorio.utadeo.edu.co:20.500.12010/14580

Acceso en línea:

https://doi.org/10.1016/j.heliyon.2020.e05278
http://hdl.handle.net/20.500.12010/14580

Palabra clave:

Bioinformatics
Immunology
Computer-aided drug design
Drug binding
Infectious disease
Viral protein
Viruses
SARS-CoV-2
Receptor binding domain
Virtual screening
Lead compounds
Anti-Viral drugs
COVID-19
Síndrome respiratorio agudo grave
COVID-19
SARS-CoV-2
Coronavirus

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