The multifaceted role of plasminogen in inflammation

A fine-tuned activation and deactivation of proteases and their inhibitors are involved in the execution of the inflammatory response. The zymogen/proenzyme plasminogen is converted to the serine protease plasmin, a key fibrinolytic factor by plasminogen activators including tissue-type plasminogen...

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Autores:
Tipo de recurso:
Article of investigation
Fecha de publicación:
2020
Institución:
Universidad de Bogotá Jorge Tadeo Lozano
Repositorio:
Expeditio: repositorio UTadeo
Idioma:
eng
OAI Identifier:
oai:expeditiorepositorio.utadeo.edu.co:20.500.12010/12721
Acceso en línea:
https://doi.org/10.1016/j.cellsig.2020.109761
http://hdl.handle.net/20.500.12010/12721
Palabra clave:
Plasminogen
Plasmin
Plasminogen receptor
Matrix metalloproteinase
LRP1
Toll like recepotor
Cytokine storm syndrome
Cytokine
tPA
COVID-19
DIC
Coagulation
Complement
Macrophage activation syndrome
NFkB
PAR
Síndrome respiratorio agudo grave
COVID-19
SARS-CoV-2
Coronavirus
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Abierto (Texto Completo)