Trends of mutation accumulation across global SARS-CoV-2 genomes: Implications for the evolution of the novel coronavirus

To understand SARS-CoV-2 microevolution, this study explored the genome-wide frequency, gene-wise distribution, and molecular nature of all point-mutations detected across its 71703 RNA-genomes deposited in GISAID till 21 August 2020. Globally, nsp1/nsp2 and orf7a/orf3a were the most mutation-ridden...

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Autores:
Tipo de recurso:
Article of investigation
Fecha de publicación:
2020
Institución:
Universidad de Bogotá Jorge Tadeo Lozano
Repositorio:
Expeditio: repositorio UTadeo
Idioma:
eng
OAI Identifier:
oai:expeditiorepositorio.utadeo.edu.co:20.500.12010/15619
Acceso en línea:
https://doi.org/10.1016/j.ygeno.2020.11.003
http://hdl.handle.net/20.500.12010/15619
Palabra clave:
SARS-CoV-2
Genome-wide mutations
Transition
Transversion
Nonsynonymous and synonymous mutations
Microevolution
COVID-19 (Enfermedad)
Infecciones por coronavirus
Vacunas - Pruebas
Rights
License
Abierto (Texto Completo)