Promising inhibitors targeting Mpro: an ideal strategy for anti- SARS-CoV-2 drug discovery

Recently, Dai W et al. published a study on Science,1 in which the two lead compounds 11a and 11b were designed and synthesized based on the features of a key enzyme Mpro of SARSCoV-2 (Fig. 1). In particular, compound 11a is a potential drug candidate for coronavirus disease 2019 (COVID-19) with str...

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Autores:
Tipo de recurso:
Article of investigation
Fecha de publicación:
2020
Institución:
Universidad de Bogotá Jorge Tadeo Lozano
Repositorio:
Expeditio: repositorio UTadeo
Idioma:
eng
OAI Identifier:
oai:expeditiorepositorio.utadeo.edu.co:20.500.12010/14043
Acceso en línea:
https://doi.org/10.1038/s41392-020-00291-8
http://hdl.handle.net/20.500.12010/14043
Palabra clave:
Targeting Mpro
Anti SARS-CoV-2
Drug discovery
Síndrome respiratorio agudo grave
COVID-19
SARS-CoV-2
Coronavirus
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