The cholesterol metabolite 27-hydroxycholesterol inhibits SARS-CoV-2 and is markedly decreased in COVID-19 patients

There is an urgent need to identify antivirals against the coronavirus SARS-CoV-2 in the current COVID-19 pandemic and to contain future similar emergencies early on. Specific side-chain cholesterol oxidation products of the oxysterols family have been shown to inhibit a large variety of both envelo...

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Autores:

Tipo de recurso:

Article of investigation

Fecha de publicación:

2020

Institución:

Universidad de Bogotá Jorge Tadeo Lozano

Repositorio:

Expeditio: repositorio UTadeo

Idioma:

eng

OAI Identifier:

oai:expeditiorepositorio.utadeo.edu.co:20.500.12010/14027

Acceso en línea:

https://doi.org/10.1016/j.redox.2020.101682
http://hdl.handle.net/20.500.12010/14027

Palabra clave:

Coronavirus
SARS-CoV-2
COVID-19
HCoV-OC43
Cholesterol
Oxysterols
27-Hydroxycholesterol
Síndrome respiratorio agudo grave
COVID-19
SARS-CoV-2
Coronavirus

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