Effect of linagliptin vs Placebo on major cardiovascular events in adults with type 2 Diabetes and high cardiovascular and renal risk The CARMELINA Randomized Clinical Trial

Importance Type 2 diabetes is associated with increased cardiovascular (CV) risk. Prior trials have demonstrated CV safety of 3 dipeptidyl peptidase 4 (DPP-4) inhibitors but have included limited numbers of patients with high CV risk and chronic kidney disease. Objective To evaluate the effect of li...

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Autores:
Rosenstock, Julio
Perkovic, Vlado
Johansen, Odd Erik
Cooper, Mark E.
Kahn, Steven E.
Marx, Nikolaus
Alexander, John H.
Pencina, Michael
Toto, Robert D.
Wanner, Christoph
Zinman, Bernard
Juergen Woerle, Hans
Baanstra, David
Pfarr, Egon
Schnaidt, Sven
Meinicke, Thomas
George, Jyothis T.
von Eynatten, Maximilian
McGuire, Darren K.
Aroca-Martínez, Gustavo
Tipo de recurso:
Fecha de publicación:
2019
Institución:
Universidad Simón Bolívar
Repositorio:
Repositorio Digital USB
Idioma:
eng
OAI Identifier:
oai:bonga.unisimon.edu.co:20.500.12442/15719
Acceso en línea:
https://hdl.handle.net/20.500.12442/15719
https://www.webofscience.com/wos/woscc/full-record/WOS:000455606000016
Palabra clave:
HEART-FAILURE
KIDNEY-DISEASE
GFR DECLINE
END-POINT
OUTCOMES
SITAGLIPTIN
DEATH
SAXAGLIPTIN
MORTALITY
CKD
Rights
closedAccess
License
Attribution-NonCommercial-NoDerivs 3.0 United States