The Role of the Nuclear Envelope Protein MAN1 in Mesenchymal Stem Cell Differentiation

Mutations in MAN1, a protein of the nuclear envelope, cause bone phenotypes characterized by hyperostosis. The mechanism of this proosteogenic phenotype remains unknown. We increased and decreased MAN1 expression in mesenchymal stem cells (MSC) upon which standard osteogenic and adipogenic different...

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Autores:

Bermeo, Sandra
Al-Saedi, Ahmed
Kassem, Moustapha
Vidal, Christopher
Duque, Gustavo

Tipo de recurso:

Fecha de publicación:

2017

Institución:

Universidad Simón Bolívar

Repositorio:

Repositorio Digital USB

Idioma:

eng

OAI Identifier:

oai:bonga.unisimon.edu.co:20.500.12442/1897

Acceso en línea:

http://hdl.handle.net/20.500.12442/1897

Palabra clave:

Mesenchymal stem cells
Osteoblastogenesis
Adipogenesis
Man1
Lamin A

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License

Licencia de Creative Commons Reconocimiento-NoComercial-CompartirIgual 4.0 Internacional