The YAP/TAZ Signaling Pathway in the Tumor Microenvironment and Carcinogenesis: Current Knowledge and Therapeutic Promises
The yes-associated protein (YAP) and the transcriptional coactivator with PDZ-binding motif (TAZ) are transcriptional coactivators, members of the Hippo signaling pathway, which play a critical role in cell growth regulation, embryonic development, regeneration, proliferation, and cancer origin and...
- Autores:
-
Ortega, Ángel
Vera, Ivana
Diaz, Maria P.
Navarro, Carla
Rojas, Milagros
Torres, Wheeler
Parra, Heliana
Salazar, Juan
De Sanctis, Juan B.
Bermúdez, Valmore
- Tipo de recurso:
- Fecha de publicación:
- 2022
- Institución:
- Universidad Simón Bolívar
- Repositorio:
- Repositorio Digital USB
- Idioma:
- eng
- OAI Identifier:
- oai:bonga.unisimon.edu.co:20.500.12442/9506
- Palabra clave:
- YAP/TAZ
Hippo signaling pathway
carcinogenesis
Tumor microenvironment
neoplastic stem cells
cell proliferation
drug resistance
chemoresistance
immunotherapy
- Rights
- openAccess
- License
- Attribution-NonCommercial-NoDerivatives 4.0 Internacional