Common interacting genetic variation shapes susceptibility to type 1 diabetes in a Colombian Caribbean community: In search of shared genetic markers

In summary, our study outlines oligogenic common variation underpinning the susceptibility to develop T1D. These genetic polymorphisms are also shared by patients suffering from other diseases such as LN and JIA, indicating that the shared genetic architecture defined by pleiotropy and epistasis sha...

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Autores:

Garavito-De Egea, Gloria
Domínguez-Vargas, Alex
Vélez, Jorge I.
Aroca, Gustavo
Fang, Luis
Navarro-Quiroz, Elkin
Espitaleta, Zilac
Del Toro-Camargo, Kenny
Martínez-Ariza, Leticia
González-Vargas, Tatiana
García, Susana
Arcos-Burgos, Mauricio

Tipo de recurso:

Fecha de publicación:

2024

Institución:

Universidad Simón Bolívar

Repositorio:

Repositorio Digital USB

Idioma:

eng

OAI Identifier:

oai:bonga.unisimon.edu.co:20.500.12442/14702

Acceso en línea:

https://hdl.handle.net/20.500.12442/14702
https://doi.org/10.1016/j.gendis.2023.06.027
https://www.sciencedirect.com/science/article/pii/S2352304223003392?via%3Dihub

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Rights

openAccess

License

Attribution-NonCommercial-NoDerivs 3.0 United States