Lamin A expression in circulating osteoprogenitors as a potential biomarker for frailty: The Nepean Osteoporosis and Frailty (NOF) Study

Lamin A is a protein of the nuclear lamina. Low levels of lamin A expression are associated with osteosarcopenia in mice. In this study, we hypothesized that low lamin A expression is also associated with frailty in humans. We aimed to develop a non-invasive method to quantify lamin A expression in...

Full description

Autores:

Al Saedi⁠, Ahmed
Gunawardene, Piumali
Bermeo, Sandra
Vogrin, Sara
Boersma, Derek
Phu, Steven
Singh⁠, Lakshman
Suriyaarachchi, Pushpa
Duque, Gustavo

Tipo de recurso:

Fecha de publicación:

2018

Institución:

Universidad Simón Bolívar

Repositorio:

Repositorio Digital USB

Idioma:

eng

OAI Identifier:

oai:bonga.unisimon.edu.co:20.500.12442/1808

Acceso en línea:

http://hdl.handle.net/20.500.12442/1808

Palabra clave:

Lamin A
Aging
Frailty
COP cells
Circulating osteoprogenitors
Flow cytometry

Rights

License

Licencia de Creative Commons Reconocimiento-NoComercial-CompartirIgual 4.0 Internacional