Mechanisms of palmitate-induced lipotoxicity in osteocytes
Background: Lipotoxicity is defined as cellular toxicity observed in the presence of an abnormal accumulation of fat and adipocyte-derived factors in non-fat tissues. Palmitic acid (PA), an abundant fatty acid in the bone marrow and particularly in osteoporotic bones, affects osteoblastogenesis and...
- Autores:
-
Al Saedi, Ahmed
Bermeo, Sandra
Plotkin, Lilian
Myers, Damian E.
Duque, Gustavo
- Tipo de recurso:
- Fecha de publicación:
- 2019
- Institución:
- Universidad Simón Bolívar
- Repositorio:
- Repositorio Digital USB
- Idioma:
- eng
- OAI Identifier:
- oai:bonga.unisimon.edu.co:20.500.12442/3607
- Acceso en línea:
- https://hdl.handle.net/20.500.12442/3607
- Palabra clave:
- Palmitic acid
Osteocytes
Lipotoxicity
Fatty acids
Osteoporosis
Apoptosis
Autophagy
- Rights
- License
- Attribution-NonCommercial-NoDerivatives 4.0 Internacional