Engineering a single-chain antibody against Trypanosoma cruzi metacyclic trypomastigotes to block cell invasion
Trypanosoma cruzi is a flagellate protozoan pathogen that causes Chagas disease. Currently there is no preventive treatment and the efficiency of the two drugs available is limited to the acute phase. Therefore, there is an unmet need for innovative tools to block transmission in endemic areas. In t...
- Autores:
-
Kalempa Demeu, Lara Maria
Jahn Soares, Rodrigo
Severo Miranda, Juliana
Pacheco-Lugo, Lisandro A.
Gonçalves Oliveira, Kelin
Cortez Plaza, Cristian Andrés
Billiald, Philippe
Ferreira de Moura, Juliana
Yoshida, Nobuko
Magalhães Alvarenga, Larissa
Duarte DaRocha, Wanderson
- Tipo de recurso:
- Fecha de publicación:
- 2019
- Institución:
- Universidad Simón Bolívar
- Repositorio:
- Repositorio Digital USB
- Idioma:
- eng
- OAI Identifier:
- oai:bonga.unisimon.edu.co:20.500.12442/4168
- Acceso en línea:
- https://hdl.handle.net/20.500.12442/4168
- Palabra clave:
- Trypanosoma cruzi
Parasitic diseases
Periplasm
Chagas disease
Protein extraction
Protozoan infections
Sequence databases
Trypomastigotes
- Rights
- License
- Attribution-NonCommercial-NoDerivatives 4.0 Internacional