In Silico Repositioning of Dopamine Modulators with Possible Application to Schizophrenia: Pharmacophore Mapping, Molecular Docking and Molecular Dynamics Analysis
We have performed theoretical calculations with 70 drugs that have been considered in 231 clinical trials as possible candidates to repurpose drugs for schizophrenia based on their interactions with the dopaminergic system. A hypotheis of shared pharmacophore features was formulated to support our c...
- Autores:
-
Mejia-Gutierrez, Melissa
- Tipo de recurso:
- Fecha de publicación:
- 2020
- Institución:
- Universidad del Atlántico
- Repositorio:
- Repositorio Uniatlantico
- Idioma:
- eng
- OAI Identifier:
- oai:repositorio.uniatlantico.edu.co:20.500.12834/1158
- Acceso en línea:
- https://hdl.handle.net/20.500.12834/1158
- Palabra clave:
- Rights
- openAccess
- License
- http://creativecommons.org/licenses/by-nc/4.0/