Caracterización de la función de las enzimas Ten Eleven Translocation (TETs) humanas en la desmetilación del DNA inducida por altos niveles de glucosa

Introduction The process of DNA demethylation was found necessary for various processes, for example, the maturation of gametes and zygote. However, the underlying mechanisms to the demethylation were not known and for a long time a passive mechanism, due to lack of maintenance, was considered as th...