Dihydroorotate dehydrogenase of Toxoplasma gondii - kinetic characterization and intracellular localization

The pyrimidine biosynthesis patway in the protozoan pathogen Toxoplosma gondii is essenial for parasite growth during infection. To investigate the properties of Dihydroorotate dehydrogenase (TgDHOD. TgDHOD exhibited a specific activity of 83.8 U/mg, a kcat of 89.2 sec-1 ± 1.5. a Km = 60.3 ±0.002 æM...

Full description

Autores:

Hortua Triana, Miryam Andrea

Tipo de recurso:

Doctoral thesis

Fecha de publicación:

2010

Institución:

Universidad de los Andes

Repositorio:

Séneca: repositorio Uniandes

Idioma:

eng

OAI Identifier:

oai:repositorio.uniandes.edu.co:1992/7764

Acceso en línea:

http://hdl.handle.net/1992/7764

Palabra clave:

Dihydroorotate dehydrogenase - Investigaciones
Toxoplasma gondii - Investigaciones
Pirimidinas - Biosíntesis - Investigaciones
Plástidos - Investigaciones
Biología

Rights

openAccess

License

http://creativecommons.org/licenses/by-nc-sa/4.0/