shRNA desing based on natural and drug induced variability targeting conserved regions from HIV reverse transcriptase

Inhibition of HIV-1 by RNA interference can be achieved by the expression of short hairpin RNAs (shRNAs) targeting conserved sequences. We designed shRNAs against HIV-1 reverse transcriptase considering the variability of conserved regions within the retrovirus reverse transcriptase conserved domain...

Full description

Autores:

Méndez Ortega, María Catalina

Tipo de recurso:

Fecha de publicación:

2010

Institución:

Universidad de los Andes

Repositorio:

Séneca: repositorio Uniandes

Idioma:

eng

OAI Identifier:

oai:repositorio.uniandes.edu.co:1992/11137

Acceso en línea:

http://hdl.handle.net/1992/11137

Palabra clave:

VIH - Investigaciones
Interferencia de ARN - Investigaciones
Terapia de gen - Investigaciones
Terapia antirretroviral altamente activa - Investigaciones
Biología

Rights

openAccess

License

http://creativecommons.org/licenses/by-nc-sa/4.0/