Daptomycin resistance in enterococcus faecium can be delayed by disruption of the LiaFSR stress response pathway

The LiaFSR signaling pathway plays a major role in mediating daptomycin (DAP) resistance for both Enterococcus faecalis and Enterococcus faecium. LiaFSR inhibition induces DAP hypersusceptibility but could also potentially delay the acquisition of DAP resistance in a combinatorial therapy of DAP wit...

Full description

Autores:
Prater, Amy G.
Mehta, Heer H.
Beabout, Kathryn
Supandy, Adeline
Miller, William R.
Tran, Truc T.
Arias, Cesar A.
Shamoo, Yousif
Tipo de recurso:
Article of journal
Fecha de publicación:
2021
Institución:
Universidad El Bosque
Repositorio:
Repositorio U. El Bosque
Idioma:
eng
OAI Identifier:
oai:repositorio.unbosque.edu.co:20.500.12495/6719
Acceso en línea:
http://hdl.handle.net/20.500.12495/6719
https://doi.org/10.1128/AAC.01317-20
Palabra clave:
Enterococo
Resistencia antibiótica
Daptomicina
Evolución de la resistencia a los medicamentos
Enterococcus
Antibiotic resistance
Daptomycin
Drug resistance evolution
Rights
openAccess
License
Attribution-NoDerivatives 4.0 Internacional