Identification of circulating tumor DNA for the early detection of small-cell lung cancer

Circulating tumor DNA (ctDNA) is emerging as a key potential biomarker for post-diagnosis surveillance but it may also play a crucial role in the detection of pre-clinical cancer. Small-cell lung cancer (SCLC) is an excellent candidate for early detection given there are no successful therapeutic op...

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Autores:

Fernandez-Cuesta, Lynnette
Avogbe, Patrice Hodonou
Leblay, Noemie
Delhomme, Tiffany M.
Gaborieau, Valerie
Abedi-Ardekani, Behnoush
Chanudet, Estelle
Olivier, Magali
Zaridze, David
Mukeria, Anush
Vilensky, Marta
Holcatova, Ivana
Polesel, Jerry
Simonato, Lorenzo
Canova, Cristina
Lagiou, Pagona
Brambilla, Christian
Byrnes, Graham
Scelo, Ghislaine
Le Calvez-Kelm, Florence
McKay, James D.
Brennan, Paul
Brambilla, Elisabeth
Perdomo Lara, Sandra Janneth

Tipo de recurso:

Fecha de publicación:

2016

Institución:

Universidad El Bosque

Repositorio:

Repositorio U. El Bosque

Idioma:

eng

OAI Identifier:

oai:repositorio.unbosque.edu.co:20.500.12495/1611

Acceso en línea:

http://hdl.handle.net/20.500.12495/1611
https://doi.org/10.1016/j.ebiom.2016.06.032

Palabra clave:

Small-Cell lung cancer
TP53 mutations
Early detection
Screening
Ácidos nucleicos libres de células
ADN tumoral circulante
Carcinoma pulmonar de células pequeñas
Genes supresores de tumor
Diagnóstico precoz

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Attribution-NonCommercial-NoDerivatives 4.0 International