A novel phosphodiesterase of the GdpP family modulates cyclic di-AMP levels in response to cell membrane stress in daptomycin-resistant enterococci

Substitutions in the LiaFSR membrane stress pathway are frequently associated with the emergence of antimicrobial peptide resistance in both Enterococcus faecalis and Enterococcus faecium Cyclic di-AMP (c-di-AMP) is an important signal molecule that affects many aspects of bacterial physiology, incl...

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Autores:
Wang, Xu
Davlieva, Milya
Reyes, Jinnethe
Panesso, Diana
Arias, Cesar A.
Shamoo, Yousif
Tipo de recurso:
Article of journal
Fecha de publicación:
2020
Institución:
Universidad El Bosque
Repositorio:
Repositorio U. El Bosque
Idioma:
eng
OAI Identifier:
oai:repositorio.unbosque.edu.co:20.500.12495/5121
Acceso en línea:
http://hdl.handle.net/20.500.12495/5121
https://doi.org/10.1128/aac.01422-16
Palabra clave:
Enterococcus faecalis
Enterococcus faecium
GdpP
LiaFSR
C-di-AMP
Cyclic dinucleotide
Daptomycin
Enterococci
Membrane stress
Rights
openAccess
License
Acceso abierto