A liaF codon deletion abolishes daptomycin bactericidal activity against vancomycin-resistant enterococcus faecalis

The genetic bases for antibiotic tolerance are obscure. Daptomycin (DAP) is a lipopeptide antibiotic with bactericidal activity against enterococci. Using time-kill assays, we provide evidence for the first time that a deletion of isoleucine in position 177 of LiaF, a member of the three-component r...

Full description

Autores:

Munita, Jose M.
Tran, Truc T.
Diaz, Lorena
Panesso, Diana
Reyes, Jinnethe
Murray, Barbara E.
Arias, Cesar A.

Tipo de recurso:

Article of journal

Fecha de publicación:

2013

Institución:

Universidad El Bosque

Repositorio:

Repositorio U. El Bosque

Idioma:

eng

OAI Identifier:

oai:repositorio.unbosque.edu.co:20.500.12495/3555

Acceso en línea:

http://hdl.handle.net/20.500.12495/3555
https://doi.org/10.1128/aac.00021-13
https://repositorio.unbosque.edu.co

Palabra clave:

Enterococcus faecalis
Vancomicina
Daptomicina

Rights

openAccess

License

Acceso abierto