Comprehensive genomic profile of heterogeneous long follow-up triple-negative breast cancer and its clinical characteristics shows DNA repair deficiency has better prognostic
Triple-negative breast cancer (TNBC) presents a marked diversity at the molecular level, which promotes a clinical heterogeneity that further complicates treatment. We performed a detailed whole exome sequencing profile of 29 Mexican patients with long follow-up TNBC to identify genomic alterations...
- Autores:
-
Rojas-Jiménez, Ernesto
Mejía-Gómez, Javier César
Díaz-Velásquez, Clara Estela
Quezada-Urbán, Rosalía
Gregorio, Héctor Martínez
Vallejo Lecuona, Fernando
De La Cruz Montoya, Aldo Hugo
Reyes, Fany Iris Porras
Pérez-Sánchez, Víctor Manuel
Maldonado-Martinez, Hector Aquiles
Robles-Estrada, Maybelline
Bargalló-Rocha, Enrique
Cabrera-Galeana, Paula
Ramos-Ramírez, Maritza
Chirino, Yolanda I
Herrera, Luis Alonso
Terrazas, Luis I.
Oliver, Javier
Frecha, Cecilia A.
Perdomo Lara, Sandra Janneth
Vaca Paniagua, Felipe
- Tipo de recurso:
- Article of journal
- Fecha de publicación:
- 2020
- Institución:
- Universidad El Bosque
- Repositorio:
- Repositorio U. El Bosque
- Idioma:
- eng
- OAI Identifier:
- oai:repositorio.unbosque.edu.co:20.500.12495/5187
- Palabra clave:
- Triple-negative breast cancer
Whole exome sequencing
WES
Treatment
Somatic mutation
Mutational signatures
- Rights
- openAccess
- License
- Attribution 4.0 International