Efficacy of ceftaroline against methicillin-susceptible Staphylococcus aureus exhibiting the cefazolin high-inoculum effect in a rat model of endocarditis
Certain Staphylococcus aureus strains exhibit an inoculum effect (InE) with cefazolin (CFZ) that has been associated with therapeutic failures in high-inoculum infections. We assessed the in vitro activities of ceftaroline (CPT), CFZ, and nafcillin (NAF) against 17 type A β-lactamase (βla)-producing...
- Autores:
-
Singh, Kavindra V.
Tran, Truc T.
Nannini, Esteban
Tam, Vincent
Arias, Cesar A
Murray, Barbara
- Tipo de recurso:
- Fecha de publicación:
- 2017
- Institución:
- Universidad El Bosque
- Repositorio:
- Repositorio U. El Bosque
- Idioma:
- eng
- OAI Identifier:
- oai:repositorio.unbosque.edu.co:20.500.12495/2319
- Palabra clave:
- Infecciones Bacterianas
Antibacterianos
Antibióticos penicilinos
β-lactamase
Staphylococcus aureus
Ceftaroline
Endocarditis
- Rights
- License
- Acceso cerrado