Mechanistic insights into the differential efficacy of Daptomycin Plus β-Lactam combinations against Daptomycin-Resistant Enterococcus faecium

Background The combination of daptomycin (DAP) plus ampicillin (AMP), ertapenem (ERT), or ceftaroline has been demonstrated to be efficacious against a DAP-tolerant Enterococcus faecium strain (HOU503). However, the mechanism for the efficacy of these combinations against DAP-resistant (DAP-R) E. fa...

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Autores:
Kebriaei, Razieh
Stamper, Kyle
Singh, Kavindra
Khan, Ayesha
Rice, Seth A.
Dinh, An Q
Tran, Truc T.
Murray, Barbara E.
Arias, César A.
Rybak, Michael Joseph
Tipo de recurso:
Article of journal
Fecha de publicación:
2020
Institución:
Universidad El Bosque
Repositorio:
Repositorio U. El Bosque
Idioma:
eng
OAI Identifier:
oai:repositorio.unbosque.edu.co:20.500.12495/5317
Acceso en línea:
http://hdl.handle.net/20.500.12495/5317
https://doi.org/10.1093/infdis/jiaa319
Palabra clave:
Vancomycin-resistant E. faecium
E. faecium
Daptomycin, β-lactam
PBP
Rights
openAccess
License
Acceso abierto