Influence of Inoculum effect on the efficacy of daptomycin monotherapy and in combination with β-Lactams against daptomycin-susceptible enterococcus faecium Harboring LiaSR Substitutions

Enterococcus faecium isolates that harbor LiaFSR substitutions but are phenotypically susceptible to daptomycin (DAP) by current breakpoints are problematic, since predisposition to resistance may lead to therapeutic failure. Using a simulated endocardial vegetation (SEV) pharmacokinetic/pharmacodyn...

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Autores:: Kebriaei, Razieh
Rice, Seth A.
Singh, Kavindra V.
Stamper, Kyle C.
Rafael Rios
Diaz, Lorena
Dinh, An Q.
Murray, Barbara
Munita, Jose M.
Arias, Cesar A
Rybak, Michael
Tran, Truc T.

Tipo de recurso:

Fecha de publicación:: 2018

Institución:: Universidad El Bosque

Repositorio:: Repositorio U. El Bosque

Idioma:: eng