2-Mercaptomethyl-thiazolidines use conserved aromatic-S interactions to achieve broad-range inhibition of metallo-β-lactamases
Infections caused by multidrug resistant (MDR) bacteria are a major public health threat. Carbapenems are among the most potent antimicrobial agents that are commercially available to treat MDR bacteria. Bacterial production of carbapenem-hydrolysing metallo-b-lactamases (MBLs) challenges their safe...
- Autores:
-
Rossi, Maria Agustina
Martinez, Veronica
Hinchliffe, Philip
Mojica, Maria F.
Castillo, Valerie
Moreno, Diego M.
Smith, Ryan
Spellberg, Brad
Drusano, George L.
Banchio, Claudia
Bonomo, Robert A.
Spencer, James
Vila, Alejandro J.
Mahler, Graciela
- Tipo de recurso:
- Article of journal
- Fecha de publicación:
- 2021
- Institución:
- Universidad El Bosque
- Repositorio:
- Repositorio U. El Bosque
- Idioma:
- eng
- OAI Identifier:
- oai:repositorio.unbosque.edu.co:20.500.12495/6193
- Palabra clave:
- Compuestos orgánicos
Interacciones aromáticas
Reacciones químicas
- Rights
- openAccess
- License
- Atribución-NoComercial 3.0 Internacional