A Comparison of Lymphoid and Myeloid Cells Derived from Human Hematopoietic Stem Cells Xenografted into NOD-Derived Mouse Strains

Humanized mice are an invaluable tool for investigating human diseases such as cancer, infectious diseases, and graft-versus-host disease (GvHD). However, it is crucial to understand the strengths and limitations of humanized mice and select the most appropriate model. In this study, we describe the...

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Autores:
Gutiérrez-Barbosa, Hernando
Medina-Moreno, Sandra
Perdomo-Celis, Federico
Davis, Harry
Coronel-Ruiz, Carolina
Zapata, Juan C.
Chua, Joel V.
Tipo de recurso:
Article of journal
Fecha de publicación:
2023
Institución:
Universidad El Bosque
Repositorio:
Repositorio U. El Bosque
Idioma:
eng
OAI Identifier:
oai:repositorio.unbosque.edu.co:20.500.12495/11103
Acceso en línea:
http://hdl.handle.net/20.500.12495/11103
https://doi.org/10.3390/microorganisms11061548
Palabra clave:
Humanización
Modelo de ratón humanizado
Xenoinjerto
CD34
NSG
NCG
NOG-EXL
NSG-SGM3
Linfoide
Mieloide
Humanization
Humanized mouse model
Xenograft
CD34
NSG
NCG
NOG-EXL
NSG-SGM3
Lymphoid
Myeloid
Rights
openAccess
License
Atribución 4.0 Internacional