A variable DNA recognition site organization establishes the Liar-mediated cell envelope stress response of enterococci to daptomycin

LiaR is a ‘master regulator’ of the cell envelope stress response in enterococci and many other Gram-positive organisms. Mutations to liaR can lead to antibiotic resistance to a variety of antibiotics including the cyclic lipopeptide daptomycin. LiaR is phosphorylated in response to membrane stress...

Full description

Autores:

Davlieva, Milya
Shi, Yiwen
Leonard, Paul G.
Johnson, Troy A.
Zianni, Michael R.
Arias, Cesar A.
Ladbury, John E.
Shamoo, Yousif

Tipo de recurso:

Fecha de publicación:

2015

Institución:

Universidad El Bosque

Repositorio:

Repositorio U. El Bosque

Idioma:

eng

OAI Identifier:

oai:repositorio.unbosque.edu.co:20.500.12495/1668

Acceso en línea:

http://hdl.handle.net/20.500.12495/1668
https://doi.org/10.1093/nar/gkv321

Palabra clave:

Farmacorresistencia microbiana
Daptomicina
Enterococcus faecalis

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Attribution-NonCommercial 4.0 International