Comparative study for in vitro release of metformin of two immediate-release multisource products, marketed in colombia
The objective of the study was to determine the equivalence of two multisource drug products of metformin tablets using in vitro testing. The in vitro dissolution profiles were done in phosphate buffer (pH 6.8), acetate buffer (pH 4.5), hydrochloric acid (pH 1.2) and two dissolution apparatus were u...
- Autores:
-
Pérez Guzmán, Milena
Orobio Lerma, Yenifer
Baena Aristizábal, Yolima
- Tipo de recurso:
- Article of journal
- Fecha de publicación:
- 2013
- Institución:
- Universidad Nacional de Colombia
- Repositorio:
- Universidad Nacional de Colombia
- Idioma:
- spa
- OAI Identifier:
- oai:repositorio.unal.edu.co:unal/49325
- Acceso en línea:
- https://repositorio.unal.edu.co/handle/unal/49325
http://bdigital.unal.edu.co/42782/
http://bdigital.unal.edu.co/42782/2/
- Palabra clave:
- metformina
multifuente
equivalencia
disolución in vitro
bioexención
metformin
multisource
equivalence
in vitro dissolution
biowaiver
- Rights
- openAccess
- License
- Atribución-NoComercial 4.0 Internacional