Comparative study for in vitro release of metformin of two immediate-release multisource products, marketed in colombia

The objective of the study was to determine the equivalence of two multisource drug products of metformin tablets using in vitro testing. The in vitro dissolution profiles were done in phosphate buffer (pH 6.8), acetate buffer (pH 4.5), hydrochloric acid (pH 1.2) and two dissolution apparatus were u...

Full description

Autores:
Pérez Guzmán, Milena
Orobio Lerma, Yenifer
Baena Aristizábal, Yolima
Tipo de recurso:
Article of journal
Fecha de publicación:
2013
Institución:
Universidad Nacional de Colombia
Repositorio:
Universidad Nacional de Colombia
Idioma:
spa
OAI Identifier:
oai:repositorio.unal.edu.co:unal/49325
Acceso en línea:
https://repositorio.unal.edu.co/handle/unal/49325
http://bdigital.unal.edu.co/42782/
http://bdigital.unal.edu.co/42782/2/
Palabra clave:
metformina
multifuente
equivalencia
disolución in vitro
bioexención
metformin
multisource
equivalence
in vitro dissolution
biowaiver
Rights
openAccess
License
Atribución-NoComercial 4.0 Internacional