Graft copolymers based on Poly(2-(dimethylamino)ethyl methacrylate) and Poly(ethyleneimine): synthesis and evaluation as vectors for DNA transfection

The first chapter reviews the most important aspects of the polymeric vectors used in gene therapy. This type of therapy involves the introduction of genetic material into specific cells to treat certain diseases, using vectors that mediate the cellular internalization of nucleic acids and protect t...