Vasodilatation induced by croton schiedeanus schlecht associated with metabolic way of guanylate cyclase

The EtOH extract of Croton shiedeanus Schlecht, medicinal species used by the popular tradition in Colombia for hypertension, relaxes vascular rings of Wistar rat aorta stimulated with phenylephrine (10-6 M, alpha adrenergic receptor agonist), in a dose-depending manner, with an EC50 of 1.3 × 10-5 g...