Circulating CXCR5-Expressing CD8+ T Cells Are Major Producers of IL-21 and Associate With Limited HIV Replication

ABSTRACT: Background: Despite advances made with the highly active antiretroviral therapy (HAART) in the control of the HIV 1 infection, a cure has not been achieved because of the persistence of viral reservoirs. The major HIV reservoirs remain in the lymphoid follicles because of, among other fact...