Itraconazole in combination with neutrophil depletion reduces the expression of genes related to pulmonary fibrosis in an experimental model of paracoccidioidomycosis
ABSTRACT: Itraconazole (ITC) is the drug of choice for treating paracoccidioidomycosis (PCM); nonetheless, patients with the chronic form of this mycosis develop fibrosis, a residual pulmonary abnormality, even after treatment. Recently, we observed that the depletion of neutrophils with a specific...
- Autores:
-
Puerta Arias, Juan David
Pino Tamayo, Paula Andrea
Arango Rincón, Julián Camilo
Salazar Peláez, Lina María
González Marín, Ángel Augusto
- Tipo de recurso:
- Article of investigation
- Fecha de publicación:
- 2018
- Institución:
- Universidad de Antioquia
- Repositorio:
- Repositorio UdeA
- Idioma:
- eng
- OAI Identifier:
- oai:bibliotecadigital.udea.edu.co:10495/24132
- Acceso en línea:
- http://hdl.handle.net/10495/24132
- Palabra clave:
- Itraconazole
Itraconazol
Paracoccidioidomycosis
Paracoccidioidomicosis
Neutrophils
Neutrófilos
Fibrosis
Fibrosis
Paracoccidioides
- Rights
- openAccess
- License
- http://creativecommons.org/licenses/by-nc/2.5/co/