Human macrophages differentiated in the presence of vitamin D3 restrict dengue virus infection and innate responses by downregulating mannose receptor expression

ABSTARCT: Severe dengue disease is associated with high viral loads and overproduction of pro-inflammatory cytokines, suggesting impairment in the control of dengue virus (DENV) and the mechanisms that regulate cytokine production. Vitamin D3 has been described as an important modulator of immune re...

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Autores:

Arboleda Alzate, John
Rodenhuis Zybert, Izabela A
Hernandéz López, Juan Carlos
Smit, Jolanda M
Urcuqui-Inchima, Silvio

Tipo de recurso:

Article of investigation

Fecha de publicación:

2017

Institución:

Universidad de Antioquia

Repositorio:

Repositorio UdeA

Idioma:

eng

OAI Identifier:

oai:bibliotecadigital.udea.edu.co:10495/11999

Acceso en línea:

http://hdl.handle.net/10495/11999

Palabra clave:

Cholecalciferol
Dengue
macrophages

Rights

openAccess

License

Atribución 2.5