Consumption of industrial processed foods and risk of premenopausal breast cancer among Latin American women: the PRECAMA study

ABSTRACT: Ultra-processed food intake has been linked to an increased risk of breast cancer in Western populations. No data are available in the Latin American population although the consumption of ultra-processed foods is increasing rapidly in this region. We evaluated the association of ultra-processed food intake to breast cancer risk in a case–control study including 525 cases (women aged 20–45 years) and 525 matched population-based controls from Chile, Colombia, Costa Rica and Mexico. The degree of processing of foods was classified according to the NOVA classification. Overall, the major contributors to ultra-processed food intake were ready-to-eat/heat foods (18.2%), cakes and desserts (16.7%), carbonated and industrial fruit juice beverages (16.7%), breakfast cereals (12.9%), sausages and reconstituted meat products (12.1%), industrial bread (6.1%), dairy products and derivatives (7.6%) and package savoury snacks (6.1%). Ultra-processed food intake was positively associated with the risk of breast cancer in adjusted models (OR T3-T1=1.93; 95% CI=1.11 to 3.35). Specifically, a higher risk was observed with oestrogen receptor positive breast cancer (ORT3-T1=2.44, (95% CI=1.01 to 5.90, P-trend=0.049), while no significant association was observed with oestrogen receptor negative breast cancer (ORT3-T1=1.87, 95% CI=0.43 to 8.13, P-trend=0.36). Our findings suggest that the consumption of ultraprocessed foods might increase the risk of breast cancer in young women in Latin America. Further studies should confirm these findings and disentangle specific mechanisms relating ultra-processed food intake and carcinogenic processes in the breast.

• Autores: Sánchez Vásquez, Gloria Inés; Maldonado Celis, María Elena; Romieu, Sabelle; Khandpur, Neha; Katsikari, Aikaterini; Biessy, Carine; Torres Mejía, Gabriela; Ángeles Llerenas, Angélica; Alvarado Cabrero, Isabel; Porras, Carolina; Rodríguez, Ana Cecilia; Garmendia, Maria Luisa; Chajés, Vèronique; Aglago, Elom K.; Porter, Peggy L.; Lin, MingGang; His, Mathilde; Gunter, Marc J.; Huybrechts, Inge; Rinaldi, Sabina
• Tipo de recurso: Article of investigation
• Fecha de publicación: 2022
• Institución: Universidad de Antioquia
• Repositorio: Repositorio UdeA
• Idioma: eng
• OAI Identifier: oai:bibliotecadigital.udea.edu.co:10495/33135
• Acceso en línea: https://hdl.handle.net/10495/33135
• Palabra clave: Evaluación Nutricional; Nutrition Assessment; Neoplasias de la Mama - prevención y control; Breast Neoplasms - prevention and control; Consumo de Alimentos; Food Consumption; Industria de Alimentos; Food Industry; América Latina; Latin America; Alimentos ultraprocesados; Ultra-processed food
• Rights: openAccess
• License: http://creativecommons.org/licenses/by/2.5/co/