Metabolic adaptation of two in silico mutants of Mycobacterium tuberculosis during infection

ABSTRACT: Background: Up to date, Mycobacterium tuberculosis (Mtb) remains as the worst intracellular killer pathogen. To establish infection, inside the granuloma, Mtb reprograms its metabolism to support both growth and survival, keeping a balance between catabolism, anabolism and energy supply. M...

Full description

Autores:

López Agudelo, Víctor Alonso
Baena García, Andrés
Ramírez Malule, Howard
Ochoa Cáceres, Silvia Mercedes
Barrera Robledo, Luis Fernando
Ríos Estepa, Rigoberto

Tipo de recurso:

Article of investigation

Fecha de publicación:

2017

Institución:

Universidad de Antioquia

Repositorio:

Repositorio UdeA

Idioma:

eng

OAI Identifier:

oai:bibliotecadigital.udea.edu.co:10495/12825

Acceso en línea:

http://hdl.handle.net/10495/12825

Palabra clave:

Mycobacterium tuberculosis
Análisis del plano de fase fenotípica
Modelado metabólico a escala del genoma
Reprogramación metabólica

Rights

openAccess

License

Atribución 2.5 Colombia (CC BY 2.5 CO)