Effect of BACE1-inhibited astrocytes on endothelial cells in a glutamate toxic environment

ABSTRACT: After cerebral ischemia or during several central nervous system (CNS) pathologies, exacerbated high glutamate concentration are released into the cerebral parenchyma producing a toxic environment that damages the components of the neurovascular unit (NVU) including the endothelial cells;...

Full description

Autores:

Pineda López, Lina Gisela

Tipo de recurso:

Article of investigation

Fecha de publicación:

2020

Institución:

Universidad de Antioquia

Repositorio:

Repositorio UdeA

Idioma:

eng

OAI Identifier:

oai:bibliotecadigital.udea.edu.co:10495/17671

Acceso en línea:

http://hdl.handle.net/10495/17671

Palabra clave:

Glutamic acid
Amyloid precursor protein secretases
Endothelial cells
Astrocytes
http://id.nlm.nih.gov/mesh/D053829
http://id.nlm.nih.gov/mesh/D001253
http://id.nlm.nih.gov/mesh/D018698
http://id.nlm.nih.gov/mesh/D042783

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embargoedAccess

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Atribución-NoComercial-SinDerivadas 2.5 Colombia (CC BY-NC-ND 2.5 CO)