Assessment of a modified release verapamil.HCl matrix compacts : Effect of formulation composition on the in-vitro release kinetic

ABSTRACT: Verapamil hydrochloride is a drug used to treat arrhythmias. In this study, a D-optimal mixture design with 16 runs was used to select the best combination of three polymers into a matrix that rendered an 8 h in vitro release profile of verapamil. hydrochloride (HCl) which fulfill a once-a...

Full description

Autores:

Rojas Camargo, John
Aristizábal, Julián
Sánchez, Joan

Tipo de recurso:

Article of investigation

Fecha de publicación:

2013

Institución:

Universidad de Antioquia

Repositorio:

Repositorio UdeA

Idioma:

eng

OAI Identifier:

oai:bibliotecadigital.udea.edu.co:10495/25207

Acceso en línea:

http://hdl.handle.net/10495/25207

Palabra clave:

Verapamilo
Verapamil
Dinámicas no Lineales
Nonlinear Dynamics
Diseño experimental
Experimental design
Controlled-release preparations

Rights

openAccess

License

http://creativecommons.org/licenses/by/2.5/co/