Validation and clinical application of a molecular method for the identification of Cryptococcus neoformans/Cryptococcus gattii complex DNA in human clinical specimens

ABSTRACT: The diagnosis of cryptococcosis is usually performed based on cultures of tissue or body flu-ids and isolation of the fungus, but this method may require several days. Direct microscopicexamination, although rapid, is relatively insensitive. Biochemical and immunodiagnosticrapid tests are...