Isolation and functional characterization of an acidic myotoxic phospholipase A2 from Colombian bothrops asper venom

ABSTRACT: Myotoxic phospholipases A2 (PLA2) are responsible for many clinical manifestations in envenomation by Bothrops snakes. A new myotoxic acidic Asp49 PLA2 (BaCol PLA2) was isolated from Colombian Bothrops asper venom using reverse-phase high performance liquid chromatography (RP-HPLC). BaCol...

Full description

Autores:

Posada Arias, Silvia
Rey Suárez, Paola
Pereañez Jiménez, Jaime Andrés
Acosta Silva, Cristian Javier
Rojas López, Mauricio
Delazari dos Santos, Lucilene
Ferreira Jr, Rui Seabra
Núñez Rangel, Vitelbina

Tipo de recurso:

Article of investigation

Fecha de publicación:

2017

Institución:

Universidad de Antioquia

Repositorio:

Repositorio UdeA

Idioma:

eng

OAI Identifier:

oai:bibliotecadigital.udea.edu.co:10495/23806

Acceso en línea:

http://hdl.handle.net/10495/23806

Palabra clave:

Venenos de Serpiente
Snake Venoms
Edema
Miotoxicidad
Myotoxicity
Phospholipases A2
Bothrops asper

Rights

openAccess

License

http://creativecommons.org/licenses/by/2.5/co/