Synthesis, antiprotozoal activity and cytotoxicity in U-937 macrophages of triclosan–hydrazone hybrids

ABSTRACT: The synthesis and biological activities (cytotoxicity, leishmanicidal, and trypanocidal) of 11 triclosan–hydrazone hybrids are described herein. The structure of the products was elucidated by spectral data (NMR, IR) and mass spectrometric analyses. The synthesized compounds were evaluated...

Full description

Autores:

Vergara Guira, Sebastian
Carda, Miguel
Agut, Raül
Yepes Daza, Lina Marcela
Vélez Bernal, Iván Darío
Robledo Restrepo, Sara María
Cardona Galeano, Wilson

Tipo de recurso:

Article of investigation

Fecha de publicación:

2017

Institución:

Universidad de Antioquia

Repositorio:

Repositorio UdeA

Idioma:

eng

OAI Identifier:

oai:bibliotecadigital.udea.edu.co:10495/23345

Acceso en línea:

http://hdl.handle.net/10495/23345

Palabra clave:

Leishmaniasis
Enfermedad de Chagas
Chagas Disease
Trypanosoma cruzi
Triclosán
Triclosan

Rights

openAccess

License

http://creativecommons.org/licenses/by/2.5/co/