Development of a novel formulation with hypericin to treat cutaneous leishmaniasis based on photodynamic therapy in in vitro and in vivo studies

ABSTRACT:An evaluation of the leishmanicidal activity in vitro and in vivo of hypericin, an expanded-spectrum photosensitizer found in Hypericum perforatum, is presented. Hypericin was evaluated against intracellular amastigotes in vitro of Leishmania (Viannia) panamensis. A topical formulation cont...

Full description

Autores:

Montoya Cuervo, Edwin Andrés
Daza Figueredo, Juan Alejandro
Muñoz Herrera, Diana Lorena
Ríos Ramírez, Yesmit Karina
Taylor Orozco, Viviana Milena
Cedeño, David
Vélez Bernal, Iván Darío
Echeverri López, Luis Fernando
Robledo Restrepo, Sara María

Tipo de recurso:

Article of investigation

Fecha de publicación:

2015

Institución:

Universidad de Antioquia

Repositorio:

Repositorio UdeA

Idioma:

eng

OAI Identifier:

oai:bibliotecadigital.udea.edu.co:10495/32966

Acceso en línea:

https://hdl.handle.net/10495/32966

Palabra clave:

Antracenos
Anthracenes
Línea Celular
Cell Line
Cricetinae
Leishmania
Leishmaniasis Cutánea
Leishmaniasis, Cutaneous
Perileno
Perylene
Fotoquimioterapia
Photochemotherapy
Fármacos Fotosensibilizantes
Photosensitizing Agents
Células U937
U937 Cells
Cicatrización de Heridas
Wound Healing

Rights

openAccess

License

http://creativecommons.org/licenses/by-nc-nd/2.5/co/