Brain Imaging and Blood Biomarker Abnormalities in Children With Autosomal Dominant Alzheimer Disease: A Cross-Sectional Study

ABSTRACT: Importance: Brain imaging and fluid biomarkers are characterized in children at risk for autosomal dominant Alzheimer disease (ADAD). Objective: To characterize and compare structural magnetic resonance imaging (MRI), resting-state and task-dependent functional MRI, and plasma amyloid-β (A...

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Autores:
Lopera Restrepo, Francisco Javier
Quiroz Gaviria, Yakeel Tatiana
Schultz, Aaron P.
Chen, Kewei
Protas, Hillary D.
Brickhouse, Michael
Fleisher, Adam S.
Langbaum, Jessica B.
Thiyyagura, Pradeep
Fagan, Anne M.
Shah, Aarti R.
Muniz, Martha
Arboleda Velásquez, Joseph Fitzgerald
Muñoz, Claudia
García Ospina, Gloria Patricia
Acosta Baena, Natalia
Giraldo Chica, Margarita María
Tirado Pérez, Victoria Claudia
Ramírez Castañeda, Dora Lucía
Tariot, Pierre N.
Dickerson, Bradford C.
Sperling, Reisa A.
Reiman, Eric M.
Tipo de recurso:
Article of investigation
Fecha de publicación:
2015
Institución:
Universidad de Antioquia
Repositorio:
Repositorio UdeA
Idioma:
eng
OAI Identifier:
oai:bibliotecadigital.udea.edu.co:10495/32982
Acceso en línea:
https://hdl.handle.net/10495/32982
Palabra clave:
Enfermedad de Alzheimer
Alzheimer Disease
Péptidos beta-Amiloides
Amyloid beta-Peptides
Biomarcadores
Biomarkers
Encéfalo
Brain
Mapeo Encefálico
Brain Mapping
Fragmentos de Péptidos
Peptide Fragments
Presenilina-1
Presenilin-1
Mutación
Mutation
Rights
openAccess
License
http://creativecommons.org/licenses/by-nc-nd/2.5/co/